Comparison of radionuclide lymphoscintigraphy and dynamic magnetic resonance lymphangiography for investigating extremity lymphoedema
Comparison of radionuclide lymphoscintigraphy and dynamic magnetic resonance lymphangiography for investigating extremity lymphoedema
复制标题
放射性核素淋巴闪烁显像与动态磁共振淋巴管造影检查四肢淋巴水肿的比较
DOI：
10.1002/bjs.6893
复制
发表时间：
2010-03-01
影响因子：
9.6
通讯作者：
Wang, B. -S.
中科院分区：
文献类型：
--
作者：
Liu, N. -F.;Lu, Q.;Wang, B. -S.
背景：淋巴闪烁显像广泛用于淋巴系统成像。本研究的目的是比较淋巴闪烁显像和动态磁共振淋巴管造影（MRL）在四肢淋巴水肿检查中的作用。方法：使用示踪剂（99）Tc标记的右旋糖酐对16名原发性肢体淋巴水肿患者和两名伴有淋巴水肿的Klippel-Trenaunay综合征患者进行淋巴闪烁显像检查，并使用钆贝酸二甲葡胺作为造影剂进行MRL检查。比较两种成像方法之间受影响肢体淋巴系统的形态异常和功能状态。结果。使用 MRL 对 18 个患有淋巴水肿的肢体中的 14 个进行了淋巴管成像，而使用淋巴闪烁扫描对 18 个肢体中的 1 个进行了成像。 MRL 在 17 名患者中的 16 名中检测到腹股沟淋巴结，而淋巴闪烁扫描仅在 9 名患者中发现腹股沟淋巴结。 MRL通过实时测量血管和淋巴结内的淋巴流量，比淋巴闪烁扫描更准确地揭示淋巴管和淋巴结的结构和功能异常信息。结论：动态MRL在检测四肢淋巴水肿患者淋巴系统解剖和功能异常方面比淋巴闪烁扫描更敏感和准确。
Background: Lymphoscintigraphy is widely used to image the lymphatic system. The aim of this study was to compare lymphoscintigraphy and dynamic magnetic resonance lymphangiography (MRL) in the investigation of extremity lymphoedema.Methods: Sixteen patients with primary extremity lymphoedema and two with Klippel-Trenaunay syndrome with lymphoedema were examined by lymphoscintigraphy using the tracer (99)Tc-labelled dextran, and by MRL using gadobenate dimeglumine as contrast agent. Morphological abnormalities and functional state of the lymphatic systems of affected limbs were compared between the two imaging methods. Results. Lymphatic vessels were imaged in 14 of 18 limbs with lymphoedema using MRL, compared with one of 18 using lymphoscintigraphy. MRL detected the inguinal nodes in 16 of 17 patients, whereas lymphoscintigraphy revealed inguinal nodes in only nine. MRL revealed more precise information about structural and functional abnormalities of lymph vessels and nodes than lymphoscintigraphy by real-time measurement of lymph flow in vessels and nodes.Conclusion: Dynamic MRL was more sensitive and accurate than lymphoscintigraphy in the detection of anatomical and functional abnormalities in the lymphatic system in patients with extremity lymphoedema.