Copper-catalysed three-component carboiodination of arynes: expeditious synthesis of o-alkynyl aryl iodides
Copper-catalysed three-component carboiodination of arynes: expeditious synthesis of o-alkynyl aryl iodides
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铜催化芳烃的三组分碳碘化：快速合成邻炔基芳基碘化物
DOI：
10.1039/c9cc09160b
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发表时间：
2020-01-18
影响因子：
4.9
通讯作者：
Xiao, Qing
中科院分区：
文献类型：
--
作者：
Cao, Wenxuan;Niu, Sheng-Li;Xiao, Qing
开发了一种铜催化的三组分芳炔碘炔化反应，用于快速、通用地合成邻炔基芳基碘化物。机理研究表明，该反应在铜催化下经历了两个步骤：1-碘-2-芳基乙炔的形成和芳炔插入C(sp)-I键。
A copper-catalysed three-component iodoalkynylation reaction of arynes for the expeditious and versatile synthesis of o-alkynyl aryl iodides has been developed. Mechanism research shows that the reaction goes through two steps enabled by copper catalysis: the formation of 1-iodo-2-arylacetylene and the insertion of the aryne into a C(sp)-I bond.