Equilibrating Immigration and Anthracene-Maleimide-Based Diels−Alder-Trapping of Octylmaleimide in Mixed Photo-Cross-Linked Polymer Micelles
Equilibrating Immigration and Anthracene-Maleimide-Based Diels−Alder-Trapping of Octylmaleimide in Mixed Photo-Cross-Linked Polymer Micelles
复制标题
平衡迁移和基于蒽马来酰亚胺的狄尔斯 - 混合光交联聚合物胶束中辛基马来酰亚胺的桤木捕获
作者：
Yan Liu;Min Tian;Huan Chang;Jinqiang Jiang;Xiangyang Yan;Zhaotie Liu;Zhongwen Liu
由于实际释放过程的复杂性，两亲性聚合物胶束内的疏水客体可能会泄漏出来，并在聚合物胶束粘附到所需焦点之前被其他物质捕获，从而降低了纳米载体系统的效率。为了描述这种情况，选择了两种分别带有光交联香豆素和蒽侧基的水溶性荧光两亲性无规共聚物PAV和PAA，利用发射光谱和吸收光谱技术研究了疏水辛基马来酰亚胺客体在水溶液中从PAV85%的一类光交联聚合物胶束向PAA66%的另一类光交联聚合物胶束的平衡迁移和基于马来酰亚胺-蒽的Diels-Alder捕获.
It is possible that the hydrophobic guest within amphiphilic polymer micelles may leak out and be captured by other species before polymer micelles adhere to the desired focus because of the complexity in an actual release procedure, rendering the reduced efficiency of the nanocarrier system. To describe such a scenario, two water-soluble fluorescent amphiphilic random copolymers ofPAVandPAAwith photo-cross-linkable coumarin and anthracene pendants, respectively, were chosen to investigate the equilibrating immigration and maleimide-anthracene-based Diels–Alder-trapping of hydrophobic octylmaleimide guest from one type of photo-cross-linked polymer micelles ofPAV85%to another ofPAA66%in aqueous solution using the emission and absorption spectra techniques.