Synthesis of amino-substituted 1,3-bis(tert-butyl-NNO-azoxy)benzenes -: 2.: 2-Amino and 2,4-diamino derivatives
Synthesis of amino-substituted 1,3-bis(tert-butyl-NNO-azoxy)benzenes -: 2.: 2-Amino and 2,4-diamino derivatives
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DOI：
10.1007/bf02494856
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发表时间：
1999-11-01
影响因子：
1.7
通讯作者：
Tartakovsky, VA
中科院分区：
文献类型：
--
作者：
Frumkin, AE;Churakov, AM;Tartakovsky, VA
2-溴-4，6-二氯-1，3-苯二胺的一个氨基被氧化成亚硝基，然后转化为叔丁基-硝基-偶氮氧基，得到了间-(叔丁基-氮氧基)苯胺的衍生物，即2-bromo-3-(tert-butyl-NNO-azoxy)-4，6-dichloroaniline.类似地，第二氨基被转化为叔丁基氮氧基，形成1，3-二(叔丁基-氮氧基)苯的衍生物，即3-bromo-2，4-bis(tert-butyl-NNO-azoxy)-1，5-dichlorobenzene，。后者与氨反应生成2-氨基和2，4-二氨基取代的1，3-二(叔丁基-氮氧基)苯。
Oxidation of one of the amino groups of 2-bromo-4,6-dichloro-1,3-phenylenediamine to the nitroso group followed by its conversion into the tert-butyl-NNO-azoxy group afforded a derivative of m-(tert-butyl-NNO-azoxy)aniline, viz., 2-bromo-3-(tert-butyl-NNO-azoxy)-4,6-dichloroaniline. Analogously, the second amino group was converted into the terl-butyl-NNO-azoxy group to form a derivative of 1,3-bis(tert-butyl-NNO-azoxy)benzene, viz., 3-bromo-2,4-bis(tert-butyl-NNO-azoxy)-1,5-dichlorobenzene, The reaction of the latter with ammonia yielded 2-amino- and 2,4-diamino-substituted 1,3-bis(tert-butyl-NNO-azoxy)benzenes.