Breast tumor imaging using a tiltable head SPECT camera

Breast tumor imaging using a tiltable head SPECT camera
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DOI:
10.1109/nssmic.2000.949385
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发表时间:
2000-10
期刊:
2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No.00CH37149)
影响因子:
--
通讯作者:
B. C. Pieper;J. Bowsher;M. Tornai;G. Peter;K. Greer;R. Jaszczak
B. C. Pieper;J. Bowsher;M. Tornai;G. Peter;K. Greer;R. Jaszczak
中科院分区:
其他
文献类型:
--
作者:
B. C. Pieper;J. Bowsher;M. Tornai;G. Peter;K. Greer;R. Jaszczak

文献摘要

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采用轴向倾斜头部SPECT (TH-SPECT)系统,以不同的倾斜角度对含有多个病变的可填充乳房和躯干幻象进行成像。为了模拟临床扫描中预期的直接污染和康普顿散射,包括乳房、肝脏和心肌活动。获取高计数平面图像与TH-SPECT进行对比,利用考虑倾斜几何的OS-FM算法重构TH-SPECT数据。为了表征TH-SPECT重建固有的轴向模糊效应,两个圆柱形磁盘Defrise幻影,一个大的Defrise幻影和一个小的Defrise幻影放置在可填充的乳房幻影中,以不同的倾斜角度成像。与高计数平面图像相比,30/spl度/重建的TH-SPECT图像最清晰地显示了乳房和躯干合并的可填充性幻象,其中包含两个1.15 ml病变,一个以轴向为中心,另一个靠近胸部前壁。病变信噪比和对比度提高了近3倍。
An axially Tiltable-Head SPECT (TH-SPECT) system with 2 heads was used to image fillable breast and torso phantoms containing multiple lesions at various tilt angles. Breast, liver, and myocardial activity were included in order to simulate direct contamination and Compton scattering expected in clinical scans. High count planar images were acquired for comparison with TH-SPECT, and the TH-SPECT data was reconstructed using an OS-FM algorithm which accounted for the tilted geometry. In order to characterize axial blurring effects inherent with TH-SPECT reconstructions, two cylindrical disk Defrise phantoms, one large Defrise phantom and one mini-Defrise phantom placed inside the fillable breast phantom, were imaged at various tilt angles. Reconstructions of the combined fillable breast and torso phantoms containing two 1.15 ml lesions, one centered axially and one proximal to the anterior chest wall within the breast, were most clearly visible in the 30/spl deg/ reconstructed TH-SPECT images compared to the high-count planar images, providing lesion SNR and contrast improvements of nearly three times.