The rise and fall and rise again of ammonia as a therapeutic target in HE
The rise and fall and rise again of ammonia as a therapeutic target in HE
复制标题
氨作为 HE 治疗靶点的上升、下降和再次上升
作者：
Tranah T
背景和目标：免疫细胞和肿瘤血管构成肿瘤组织中的重要元素;然而，它们在人类肿瘤（包括HCC）中的详细关系在很大程度上仍然未知。因此，我们扩展了我们以前对HCC免疫微环境的研究，并分析了免疫微环境、炎症/血管生成抑制因子表达、血管生成因子表达和肿瘤血管发现之间的关系，包括血管包裹肿瘤簇（VETC）和巨小梁增生（MTM）模式。方法与结果：我们将HCC分为四种不同的免疫血管亚型（免疫高/血管抑制[IH/AS]，免疫中/血管中[IM/AM]，免疫低/血管生成[IL/AG]和免疫低/血管低[IL/AL]）。IH/
Background and Aims: Immune cells and tumor vessels constitute important elements in tumor tissue; however, their detailed relationship in human tumors, including HCC, is still largely unknown. Consequently, we expanded our previous study on the immune microenvironment of HCC and analyzed the relationship among the immune microenvironment, inflammatory/angiostatic factor expression, angiogenic factor expression, and tumor vessel findings, including vessels encapsulating tumor clusters (VETC) and macrotrabecularmassive (MTM) patterns. Approach and Results: We classified HCC into four distinct immunovascular subtypes (immune-high/angiostatic [IH/AS], immune-mid/angio-mid [IM/AM], immune-low/angiogenic [IL/AG], and immune-low/angio-low [IL/AL]). IH/
影响因子：
29.4
作者：
Sharma, Barjesh Chander;Sharma, Praveen;Sarin, Shiv Kumar
通讯作者：
Sarin, Shiv Kumar
影响因子：
12.6
作者：
Rahimi，Robert S.;Safadi，Rifaat;Bajaj，Jasmohan S.
通讯作者：
Bajaj，Jasmohan S.