Calcium and phosphate requirements of preterm infants who require prolonged hyperalimentation.

Calcium and phosphate requirements of preterm infants who require prolonged hyperalimentation.
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需要长期高营养的早产儿对钙和磷的需求。

DOI:
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发表时间:
1980
期刊:
Journal of the American Medical Association (JAMA)
影响因子:
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通讯作者:
Clatworthy Hw
Clatworthy Hw
中科院分区:
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文献类型:
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作者:
Knight Pj;S. Buchanan;Clatworthy Hw

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早产儿需要大量的钙和磷酸盐,以维持长期高营养期间的骨骼矿化。这是不可能的供应量的钙和磷酸盐通常收购transplantarily(150 mg/kg/天的钙和80 mg/kg/天的磷酸盐)与合理体积的生理pH的单一高营养溶液。我们最近遇到磷酸钙沉淀物堵塞我们的高营养导管,因为我们试图提高钙浓度超过20 mEq的钙每升高营养溶液。当以125 mL/kg/天运行时,这种溶液提供50 mg/kg/天的钙。为了解决这个问题,我们目前正在使用两种高营养溶液-一种高钙,另一种高磷酸盐-交替运行12小时。该方案提供80 mg/kg/天的钙。
Preterm infants require large amounts of calcium and phosphate to maintain skeletal mineralization during prolonged hyperalimentation. It is impossible to supply the amount of calcium and phosphate normally acquired transplacentally (150 mg/kg/day of calcium and 80 mg/kg/day of phosphate) with reasonable volumes of a single hyperalimentation solution of a physiological pH. We recently encountered calcium phosphate precipitates plugging our hyperalimentation catheters as we tried to raise the calcium concentration above 20 mEq of calcium per liter of hyperalimentation solution. Such a solution supplies 50 mg/kg/day of calcium when run at 125 mL/kg/day. In an attempt to circumvent this problem, we are currently using two hyperalimentation solutions--one high in calcium and the other high in phosphates--run alternately for 12-hour periods. This regimen supplies 80 mg/kg/day of calcium.