MOLECULAR-GENETICS OF ANTIGENIC VARIATION
MOLECULAR-GENETICS OF ANTIGENIC VARIATION
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DOI：
10.1016/s0167-5699(05)80009-x
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发表时间：
1991-03-01
期刊：
影响因子：
--
通讯作者：
BORST, P
中科院分区：
文献类型：
--
作者：
BORST, P
抗原变异是寄生虫逃避免疫破坏的最有效策略之一。它需要一个大衣柜的表面大衣和机制，以交换一个大衣一个无关的。抗原变异的分子原理现在在细菌种--疏螺旋体和奈瑟氏球菌以及非洲锥虫组的原生动物中已被广泛了解，Piet Borst在此讨论了这三个例子。
Antigenic variation is one of the most effective strategies developed by parasites to escape immune destruction. It requires a large wardrobe of surface coats and mechanisms to exchange one coat for an unrelated one. The molecular principles of antigenic variation are now largely known in the bacterial speciesBorreliaandNeisseriaand in the protozoa of the African trypanosome group and these three examples are discussed here by Piet Borst.