Radiographic scoring method for the assessment of the severity of nutritional rickets
Radiographic scoring method for the assessment of the severity of nutritional rickets
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DOI：
10.1093/tropej/46.3.132
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发表时间：
2000-06-01
影响因子：
2
通讯作者：
Reading, JC
中科院分区：
文献类型：
--
作者：
Thacher, TD;Fischer, PR;Reading, JC
佝偻病的影像学变化具有很好的特征，但没有一种方法可以对这些变化的严重程度进行分级。因此，很难客观地比较或跟踪影像学的改善。我们前瞻性地评估了测量佝偻病严重程度的评分方法的实用性和可重复性。腕关节和膝关节x线片评分为10分，用于评估干骺端磨损和拔罐的程度以及生长板受影响的比例。分数从0分（正常）到10分（严重），以半分的增量递增。四名训练有素的医生分别在两个不同的场合对67名活动性佝偻病儿童的x光片进行评分。放射学平均评分的广泛代表与碱性磷酸酶中度相关（r = 0.58）。所有观察者对放射评分的观察者间相关性为0.84或更高，每个观察者的观察者内相关性为0.89或更高。研究人员和临床医生应该发现该评分有助于客观评估佝偻病的严重程度。
Radiographic changes of rickets are well characterized, but no method of grading the severity of these changes has been in general use. Consequently, it is difficult to compare objectively or follow radiographic improvement. We prospectively evaluated the utility and reproducibility of a scoring method for measuring the severity of rickets. A 10-point score for radiographs of wrists and knees was devised to assess the degree of metaphyseal fraying and cupping and the proportion of the growth plate affected. The score progresses in half point increments from zero (normal) to 10 points (severe). Four trained physicians independently scored radiographs on two separate occasions from 67 children with active rickets. A broad representation of mean radiographic scores was moderately correlated with alkaline phosphatase (r = 0.58). Interobserver correlation of radiographic scores was 0.84 or greater for all observer pairs and intraobserver correlation was 0.89 or greater for each observer. Researchers and clinicians should find the score useful to assess objectively the severity of rickets.