Novel approaches to surfactant administration.
Novel approaches to surfactant administration.
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DOI：
10.1155/2012/278483
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发表时间：
2012
影响因子：
1.7
通讯作者：
Donn SM
中科院分区：
文献类型：
--
作者：
Gupta S;Donn SM
20多年来，肺表面活性物质替代疗法一直是早产儿呼吸窘迫综合征的主要治疗方法。在大多数情况下，肺表面活性物质是经气管内给药，然后是机械通气。近年来，人们对无创呼吸机的兴趣与日俱增，催生了新的给药方法。本文将对这些技术和相关的临床证据进行综述。
Surfactant replacement therapy has been the mainstay of treatment for preterm infants with respiratory distress syndrome for more than twenty years. For the most part, surfactant is administered intratracheally, followed by mechanical ventilation. In recent years, the growing interest in noninvasive ventilation has led to novel approaches of administration. This paper will review these techniques and the associated clinical evidence.