The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus
The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus
复制标题
DOI：
10.3109/09637486.2014.880671
复制
发表时间：
2014-06-01
影响因子：
3.9
通讯作者：
Djalali, Mahmoud
中科院分区：
文献类型：
--
作者：
Arablou, Tahereh;Aryaeian, Naheed;Djalali, Mahmoud
目的：评估食用生姜对 2 型糖尿病患者血糖状况、血脂和一些炎症标志物的影响。方法：在一项双盲、安慰剂对照临床试验中，招募了 70 名 2 型糖尿病患者。他们随机分为生姜组和对照组。他们在 12 周内每天摄入 1600 毫克生姜，而安慰剂则摄入 1600 毫克小麦粉。干预前后测定血清糖、血脂、CRP、PGE2和TNFα。结果：与安慰剂组相比，生姜显着降低空腹血糖、HbA(1C)、胰岛素、HOMA、甘油三酯、总胆固醇、CRP 和 PGE(2) (p0.05)。结论：生姜改善了 2 型糖尿病患者的胰岛素敏感性和部分血脂水平，并降低了 CRP 和 PGE(2)。因此生姜可以被认为是预防糖尿病并发症的有效治疗方法。
Objective: To assess the effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus. Methods: In a double-blinded, placebo-controlled clinical trial, 70 type 2 diabetic patients were enrolled. They allocated randomly into ginger group and control group. They consumed 1600 mg ginger versus 1600 mg wheat flour placebo daily for 12 weeks. Serum sugar, lipids, CRP, PGE2 and TNF alpha were measured before and after intervention. Results: Ginger reduced fasting plasma glucose, HbA(1C), insulin, HOMA, triglyceride, total cholesterol, CRP and PGE(2) significantly compared with placebo group (p0.05). Conclusion: Ginger improved insulin sensitivity and some fractions of lipid profile, and reduced CRP and PGE(2) in type 2 diabetic patients. Therefore ginger can be considered as an effective treatment for prevention of diabetes complications.