QUANTITATIVE MICRORADIOGRAPHIC STUDIES OF NORMAL AND OSTEOPOROTIC BONE.

QUANTITATIVE MICRORADIOGRAPHIC STUDIES OF NORMAL AND OSTEOPOROTIC BONE.
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正常骨和骨质疏松骨的定量显微放射学研究。

DOI:
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发表时间:
1965
期刊:
Journal of Bone and Joint Surgery. American volume
影响因子:
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通讯作者:
J. Gershon
J. Gershon
中科院分区:
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文献类型:
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作者:
J. Jowsey;D. Phil.;P. Kelly;B. Riggs;A. J. Bianco;D. Scholz;J. Gershon

文献摘要

被引文献

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定量显微放射学已发展用于研究骨转换,并已应用于研究正常和骨质疏松的人骨。证据表明,这种方法是可重复的,并提供了一个准确的测量骨形成和吸收。结果表明,大多数骨质疏松症患者的骨与正常骨的不同之处在于吸收量的增加。骨形成水平一般正常;然而,在库欣综合征中,皮质类固醇治疗和固定后,骨形成减少。
Quantitative microradiography has been developed for studying bone turnover and has been applied to a study of normal and osteoporotic human bone. Evidence is presented that this method is reproducible and provides an accurate measure of bone formation and resorption. It was demonstrated that bone from the majority of osteoporotic patients differs from normal bone by an increase in the amount of resorption. Bone formation levels are generally normal; however, in Cushing's syndrome, after corticosteroid therapy, and after immobilization, bone formation decreases.