A study of artefacts in simultaneous PET and MR imaging using a prototype MR compatible PET scanner
A study of artefacts in simultaneous PET and MR imaging using a prototype MR compatible PET scanner
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DOI：
10.1088/0031-9155/44/8/312
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发表时间：
1999-08-01
影响因子：
3.5
通讯作者：
Cherry, SR
中科院分区：
文献类型：
--
作者：
Slates, RB;Farahani, K;Cherry, SR
我们已经评估了使用小型MR兼容PET扫描仪(McPET)同时执行正电子发射断层扫描(PET)和磁共振成像(MRI)时可能出现伪影的可能性。在这些实验中，我们检查MR图像中的任何主要伪影或由于磁场不均匀、射频干扰或由MR扫描仪内的PET系统操作引起的敏感性影响而导致的图像质量损失。此外，还研究了由静态和时变磁场或射频干扰引起的PET图像中可能出现的伪影。使用生物组织和T-2加权自旋回波序列来检查由于位于MR视野中的McPET扫描仪的部件(闪烁体、光纤)而产生的敏感性伪影。在采集PET数据时，研究了一系列常用的MR脉冲序列，以在PET或MR图像中寻找可能的伪影。除了使用梯度回波序列的信噪比有小的损失外，两种成像系统之间没有显著的相互作用。在场强从0.2到4.7T的不同MR系统中，也同时进行了简单模型的PET和MR成像。这些研究的结果表明，使用我们的原型MR兼容的PET扫描仪，可以同时采集PET和MR图像，而不会出现任何明显的伪影或图像质量损失。
We have assessed the possibility of artefacts that can arise in attempting to perform simultaneous positron emission tomography (PET) and magnetic resonance imaging (MRI) using a small prototype MR compatible PET scanner (McPET). In these experiments, we examine MR images for any major artefacts or loss in image quality due to inhomogeneities in the magnetic field, radiofrequency interference or susceptibility effects caused by operation of the PET system inside the MR scanner. In addition, possible artefacts in the PET images caused by the static and time-varying magnetic fields or radiofrequency interference from the MR system were investigated. Biological tissue and a T-2-weighted spin echo sequence were used to examine susceptibility artefacts due to components of the McPET scanner (scintillator, optical fibres) situated in the MR field of view. A range of commonly used MR pulse sequences was studied while acquiring PET data to look for possible artefacts in either the PET or MR images. Other than a small loss in signal-to-noise using gradient echo sequences, there was no significant interaction between the two imaging systems. Simultaneous PET and MR imaging of simple phantoms was also carried out in different MR systems with field strengths ranging from 0.2 to 4.7 T. The results of these studies demonstrate that it is possible to acquire PET and MR images simultaneously, without any significant artefacts or loss in image quality, using our prototype MR compatible PET scanner.