20 KDa homologous restriction factor of complement resembles T cell activating protein.

20 KDa homologous restriction factor of complement resembles T cell activating protein.
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20 KDa 补体同源限制因子类似于 T 细胞激活蛋白。

DOI:
10.1016/0006-291x(89)90852-8
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发表时间:
1989
影响因子:
3.1
通讯作者:
J. Kondo
J. Kondo
中科院分区:
生物学4区
文献类型:
--
作者:
H. Okada;Yoichi Nagami;Kazuhiro Takahashi;N. Okada;T. Hideshima;H. Takizawa;J. Kondo

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我们以前鉴定了一个20KDa的膜糖蛋白1F5抗原,它抑制同源补体膜攻击复合物的组装,我们将其命名为HRF 20,代表20KDa同源限制因子。从其编码碱基序列推导的氨基酸序列类似于T细胞活化蛋白,最显著的是半胱氨酸残基,其中11个中有10个占据相同的位置,总序列同源性为24.8%。此外,HRF20的单克隆抗体刺激人T细胞的增殖。
We previously identified a 20KDa membrane glycoprotein 1F5 antigen which inhibits the assembly of homologous complement membrane attack complexes and we designate it as HRF20 standing for 20KDa homologous restriction factor. The amino acid sequence deduced from its coding base sequence resembles that of T cell activating protein, most conspicuously in cysteine residues, 10 out of 11 of which occupy identical positions in an overall sequence homology of 24.8%. Furthermore, proliferation of human T cells was stimulated by monoclonal antibody to HRF20.
人红细胞裂解中的同源物种限制:具有 C8 结合能力的膜衍生蛋白充当抑制剂。
DOI: --
发表时间: 1986
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Schönermark,S;Rauterberg,EW;Shin,ML;Löke,S;Roelcke,D;Hänsch,GM
通讯作者: Hänsch,GM