Signal transduction via the growth hormone receptor.
Signal transduction via the growth hormone receptor.
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DOI:
10.1016/s0898-6568(01)00186-3
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发表时间:
2001-09
影响因子:
4.8
通讯作者:
T. Zhu;E. Goh;R. Graichen;Ling Ling-Ling;P. Lobie
中科院分区:
文献类型:
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作者:
T. Zhu;E. Goh;R. Graichen;Ling Ling-Ling;P. Lobie
Rapid progress has been made recently in the definition of growth hormone (GH) receptor signal transduction pathways. It is now apparent that many cytokines, including GH, share identical or similar signalling components to exert their cellular effects. This review provides a brief discourse on the signal transduction pathways, which have been demonstrated to be utilized by GH. The identification of such pathways provides a basis for understanding the pleiotropic actions of GH. The mechanisms by which the specific cellular effects of GH are achieved remain to be elucidated.