Canine histoplasmosis in Rio de Janeiro: natural and experimental infections.
Canine histoplasmosis in Rio de Janeiro: natural and experimental infections.
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里约热内卢的犬组织胞浆菌病：自然和实验感染。
DOI：
10.1080/02681218780000361
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Bernardo Galvão
中科院分区：
文献类型：
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作者：
V. L. Silva;M. Ferreira;Bodo Wanke;Bernardo Galvão
在里约热内卢的73只杂种狗中，有7只在用荚膜组织胞浆菌多糖菌丝体抗原进行的皮肤试验中得到阳性结果。5例阳性反应者进行了尸检，其中4例经组织病理学和培养证实为播散性组织胞浆菌病。四只健康的幼犬暴露于已知组织胞浆菌病爆发部位的土壤中10分钟，出现症状，并在暴露于暴发性组织胞浆菌病后7-14天死亡。这些实验表明狗作为组织胞浆菌病的流行病学指标和作为该疾病的实验模型的价值。
Seven of 73 mongrel dogs in Rio de Janeiro gave positive results in skin tests with a polysaccharide mycelial antigen from Histoplasma capsulatum. Five of the positive reactors were necropsied and four of them had disseminated histoplasmosis proved by histopathology and culture. Four healthy puppies exposed for 10 min to soil at the site of a known outbreak of histoplasmosis developed symptoms and died 7-14 days after exposure with fulminant histoplasmosis. These experiments show the value of dogs as epidemiological indicator of histoplasmosis and as experimental models for the disease.