Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia
Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia
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DOI:
10.1083/jcb.201901077
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发表时间:
2019-08
期刊:
影响因子:
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通讯作者:
I. Yanakieva;A. Erzberger;M. Matejčić;C. Modes;Caren Norden
中科院分区:
文献类型:
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作者:
I. Yanakieva;A. Erzberger;M. Matejčić;C. Modes;Caren Norden
Using quantitative live imaging in the developing zebrafish embryo, Yanakieva et al. show that distinct actin-dependent mechanisms position nuclei in neuroepithelia of different morphology. In curved neuroepithelia, a novel formin-dependent mechanism is discovered for which the authors propose a proof-of-principle theoretical model.