The effect of aspirin on the visual outcome of nonarteritic anterior ischemic optic neuropathy
The effect of aspirin on the visual outcome of nonarteritic anterior ischemic optic neuropathy
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DOI：
10.1016/s0002-9394(14)70448-9
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发表时间：
1996-04-01
影响因子：
4.2
通讯作者：
Arnold, AC
中科院分区：
文献类型：
--
作者：
Botelho, PJ;Johnson, LN;Arnold, AC
目得：研究阿司匹林的使用对nonarteritic前部缺血性视神经病变的视觉结局的影响：方法：这项回顾性病例对照研究包括23例患者谁使用阿司匹林定期之前和过程中的nonarteritic前部缺血性视神经病变和55例对照患者nonarteritic前部缺血性视神经病变。从初始和最终随访检查中收集Snellen视力（logMAR）和自动视野检查的平均偏差。服用阿司匹林的患者与对照组患者的比较显示，（P = 0.36），也不是随访logMAR（P = 0.95）数据差异显著，两组之间的初始结论：阿司匹林不能改善非动脉炎性前部缺血性视神经病变患者的视力预后，需要进一步研究来阐明这一问题。
PURPOSE: To examine the effect of aspirin use on the visual outcome of nonarteritic anterior ischemic optic neuropathy.METHODS: This retrospective case-controlled study included 23 patients who used aspirin regularly before and during the course of nonarteritic anterior ischemic optic neuropathy and 55 control patients with nonarteritic anterior ischemic optic neuropathy. Snellen visual acuity in logMAR and mean deviation on automated perimetry were compiled from the initial and final follow-up examinations.RESULTS: The comparisons of patients who took aspirin with control patients disclosed that neither initial logMAR (P = .36) nor the follow-up logMAR (P = .95) data differed significantly, There was no significant difference between the groups for the initial (P = .60) and the follow-up mean deviation (P = .41).CONCLUSION: Aspirin use does not improve the visual outcome of patients with nonarteritic anterior ischemic optic neuropathy, Additional studies are needed to further elucidate this issue.