Severe Vascular Complications Caused by Facial Autologous Fat Grafting: A Critical Review.
Severe Vascular Complications Caused by Facial Autologous Fat Grafting: A Critical Review.
复制标题
面部自体脂肪移植引起的严重血管并发症：批判性回顾。
DOI：
10.1097/sap.0000000000002691
复制
发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
Yi chenggang
中科院分区：
文献类型：
--
作者：
Wang kai;Yi chenggang
背景
血管栓塞是自体脂肪移植术后最严重的并发症。随着脂肪移植在全球范围内的增加，严重的血管并发症也有所增加，如眼动脉栓塞、脑动脉栓塞，甚至死亡。本文就脂肪在严重血管并发症中的作用以及脂肪移植与严重血管并发症的关系作一综述。
方法
通过评估全球报道的与面部脂肪移植相关的严重血管并发症的病例，进行了一项批判性综述。对在多个出版物中报道的重复病例进行进一步筛选。
结果
最后的检索结果是符合纳入审查标准的50份英文出版物。在文献中，共有113例脂肪引起的严重血管并发症被确认。随着时间的推移，每年报告的病例数量有所增加，自2010年以来的增幅甚至更大。眉间和太阳穴是文献中描述的最常见的严重血管并发症的部位。此外，仅有1例眼动脉栓塞和1例脑动脉栓塞成功治疗。
结论
鉴于严重血管并发症的报告病例增加，医生和患者都应密切关注面部脂肪移植的风险。由于血管栓塞症的发病机制尚不清楚，且缺乏防治指南，其有效治愈率并不理想。我们建议，预防血管栓塞是脂肪移植的首要任务，当发生严重的血管并发症时，应及时进行多学科的治疗。为了促进脂肪移植的发展，有必要在今后的研究中探索血管栓塞的机制和有效的治疗策略。
BACKGROUND
Vascular embolism is the most severe complication after autologous fat grafting. With a worldwide increase in fat grafting, there has been a rise in severe vascular complications, such as ophthalmic artery embolism, cerebral artery embolism, and even death. This article aims to review the role of fat in causing severe vascular complications and the association between fat grafting and severe vascular complications.
METHODS
A critical review was conducted by appraising the cases of severe vascular complications associated with facial fat grafting reported globally. Repeated cases that were reported in multiple publications were further screened.
RESULTS
The final search yielded 50 publications in English that met the inclusion criteria for review. A total of 113 cases of fat-induced severe vascular complications in the literature were identified. The number of cases reported yearly has increased over time, with even more significant increases since 2010. The glabella and temple are the most common sites of severe vascular complications described in the literature. In addition, only one case of ophthalmic artery embolism and one case of cerebral artery embolism have been treated successfully.
CONCLUSIONS
Given the increase in reported cases of severe vascular complications, both doctors and patients should pay careful attention to the risks of facial fat grafting. Because of the unclear mechanism of vascular embolism and the lack of guidelines for prevention and treatment, the effective cure rate is unsatisfactory. We propose that preventing vascular embolism is a priority in fat grafting and that timely, multidisciplinary treatment should be performed when severe vascular complications occur. It is necessary in future studies to explore the mechanisms of vascular embolism and effective treatment strategies to promote the development of fat grafting.
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DOI：
10.1097/iae.0b013e31826a6897
发表时间：
2012-11
期刊：
Retina
影响因子：
--
作者：
L. Xing;David Almeida;Michel J. Belliveau;H. Hollands;R. Devenyi;Alan K. Berger;J. Gale
通讯作者：
L. Xing;David Almeida;Michel J. Belliveau;H. Hollands;R. Devenyi;Alan K. Berger;J. Gale
影响因子：
2.4
作者：
Szantyr A;Orski M;Marchewka I;Szuta M;Orska M;Zapała J
通讯作者：
Zapała J
影响因子：
2.4
作者：
T. Tansatit;Hyoung-Jin Moon;Prawit Apinuntrum;Thavorn Phetudom
通讯作者：
T. Tansatit;Hyoung-Jin Moon;Prawit Apinuntrum;Thavorn Phetudom
影响因子：
6.1
作者：
Chen Yanyun;Wang Wenying;Lu Ning
通讯作者：
Lu Ning
影响因子：
6
作者：
Sarah Tolédano;Julie Zyss;S. Gerber;M. Rodallec;M. Zuber
通讯作者：
Sarah Tolédano;Julie Zyss;S. Gerber;M. Rodallec;M. Zuber