Recovery of human immunodeficiency virus from serum.
Recovery of human immunodeficiency virus from serum.
复制标题
从血清中回收人类免疫缺陷病毒。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
J. Levy
中科院分区：
文献类型：
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作者：
B. Michaelis;J. Levy
To the Editor.— Our laboratory has reported the isolation of the human immunodeficiency virus (HIV) from peripheral mononuclear blood cells (PMCs) from over 300 individuals with the acquired immunodeficiency syndrome (AIDS) or AIDS-related conditions and from asymptomatic individuals from the risk groups.1,2We have also isolated the AIDS virus from a variety of body fluids, including serum, plasma, tears, urine, saliva, and genital secretions.3,4We now report the results of a survey of serum samples from 78 randomly selected, seropositive individuals, of whom about 30% were asymptomatic. Infectious virus was recovered from the serum of 20 (25.6%) of these individuals and was generally present in low titers. Only undiluted serum (not a tenfold dilution) yielded infectious virus as detected by assays on uninfected PMCs.2In one serum sample, 25000 infectious particles per milliliter were detected as measured by end dilution of the serum. This sample came from
