IMPORTANCE OF SUPRAVITALITY IN FORENSIC MEDICINE
IMPORTANCE OF SUPRAVITALITY IN FORENSIC MEDICINE
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DOI：
10.1016/0379-0738(94)90386-7
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发表时间：
1994-12-16
影响因子：
2.2
通讯作者：
MADEA, B
中科院分区：
文献类型：
--
作者：
MADEA, B
基于对完全暂时性缺血下潜伏期、存活期和复苏期的生理学研究，超活力可被定义为在完全不可逆缺血后组织（相较于复苏期）更长的存活期。超活力主要由功能参数（对刺激的敏感性）来定义。作为超活力反应（对刺激的敏感性）基础的超活力代谢参数（无氧糖酵解的底物和代谢产物）也进行了讨论。提及了与生理状况相比的特定超活力反应模式（坎农 - 罗森布鲁斯去神经定律、对药理刺激的超敏感性、局部收缩而非传导性兴奋）。最后，将简要提及在超活力早期（潜伏期、存活期）可能诱发的形态学改变以及它们源于局部生命反应的去向。
Based on physiological investigations on latency period, survival period and resuscitation period under complete temporary ischemia, supravitality can be defined as even longer survival period of tissues (compared to the resuscitation period) after complete irreversible ischemia. Supravitality is mostly defined by functional parameters (sensitivity to excitation). Parameters of supravital metabolism (substrates and metabolites of anaerobic glycolysis) as a basis for supravital reactions (sensitivity to excitation) are discussed. Particular supravital reaction patterns in comparison to physiological conditions are mentioned (Cannon Rosenbluth's law of denervation, supersensitivity to pharmacological excitation, local contraction instead of propagated excitation). Lastly, morphological alterations which can be induced during the early supravital period (latency period, survival period) as well as their destination from local vital reactions will be briefly mentioned.