FAR-WALL PSEUDOENHANCEMENT DURING CONTRAST-ENHANCED ULTRASOUND OF THE CAROTID ARTERIES: CLINICAL DESCRIPTION AND IN VITRO REPRODUCTION
FAR-WALL PSEUDOENHANCEMENT DURING CONTRAST-ENHANCED ULTRASOUND OF THE CAROTID ARTERIES: CLINICAL DESCRIPTION AND IN VITRO REPRODUCTION
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DOI：
10.1016/j.ultrasmedbio.2011.12.019
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发表时间：
2012-04-01
影响因子：
2.9
通讯作者：
van der Steen, Antonius F. W.
中科院分区：
文献类型：
--
作者：
ten Kate, Gerrit L.;Renaud, Guillaume G. J.;van der Steen, Antonius F. W.
本研究描述了在对比增强超声（CEUS）成像的人颈动脉伪增强的存在和复制这种伪增强在体外。70例患者使用配备L9-3超声探头和SonoVue微泡造影剂的Philips iU 22超声系统进行双侧颈动脉CEUS检查。在颈动脉的CEUS中，我们发现了与主腔平行的靠近远壁的增强。这种增强的位置与平行血管的解剖位置无关。为了证实这是伪增强伪影的假设，使用与患者研究相同的超声系统、设置和造影剂，在组织模拟材料体模中重建增强。体模研究表明，在血管CEUS过程中可能存在假性增强，并且假性增强的程度受微泡的大小和浓度的影响。在血管CEUS中，识别伪影对于防止误解远壁内和近壁的增强非常重要。（电子邮件：g.l. erasmusmc.nl）（C）2012年世界医学和生物学超声联合会。
The present study describes the presence of pseudoenhancement during contrast-enhanced ultrasound (CEUS) imaging of human carotid arteries and the reproduction of this pseudoenhancement in vitro. Seventy patients underwent bilateral CEUS examination of the carotid arteries using a Philips iU22 ultrasound system equipped with a L9-3 ultrasound probe and SonoVue microbubble contrast. During CEUS of the carotid arteries, we identified enhancement in close proximity to the far wall, parallel to the main lumen. The location of this enhancement does not correlate to the anatomical location of a parallel vessel. To corroborate the hypothesis that this is a pseudoenhancement artifact, the enhancement was recreated in a tissue-mimicking material phantom, using the same ultrasound system, settings and contrast agent as the patient study. The phantom study showed that pseudoenhancement may be present during vascular CEUS and that the degree of pseudoenhancement is influenced by the size and concentration of the microbubbles. During vascular CEUS, identification of the artifact is important to prevent misinterpretation of enhancement in and near the far wall. (E-mail: g.l.tenkate@erasmusmc.nl) (C) 2012 World Federation for Ultrasound in Medicine & Biology.