Histologic assessment of healing after the use of a bioresorbable membrane in the management of buccal bone loss concomitant with periradicular surgery.
Histologic assessment of healing after the use of a bioresorbable membrane in the management of buccal bone loss concomitant with periradicular surgery.
复制标题
使用生物可吸收膜治疗伴随根周手术的颊骨丢失后愈合的组织学评估。
DOI：
10.1097/00004770-200106000-00009
复制
发表时间：
2001
影响因子：
4.2
通讯作者：
D. Witherspoon
中科院分区：
文献类型：
--
作者：
J. Douthitt;J. Gutmann;D. Witherspoon
在颊部裂开处使用生物可吸收膜后，对根周伤口愈合进行组织学和形态学评估。切除9只犬的第三和第四前磨牙，并制作颊侧缺损。牙齿被随机分配到膜或对照组。每个象限中的一颗牙齿接受膜，覆盖两个牙根。另一颗牙齿没有接受进一步的治疗，并作为对照。在两个时间段：9周和27周处死动物并对标本进行评估。27周膜组表现出显着更多的（p = 0.004）结缔组织高度比对照组或9周组。27周膜组的再生牙槽骨数量显著大于对照组（p = 0.001）和9周组。对照组的平均交界上皮测量值显著更大（p = 0.012）。当在根周手术时存在颊部缺损时，生物可吸收膜的使用增强了骨再生。
Histological and morphometric assessment of periradicular wound healing was made after the use of a bioresorbable membrane over a buccal dehiscence. The third and fourth premolar teeth of nine dogs were resected and buccal defects created. Teeth were assigned randomly to the membrane or control group. One tooth in each quadrant received a membrane, covering both roots. The other tooth received no further treatment and served as a control. The animals were killed and specimens were assessed at two time periods: 9 wk and 27 wk. The 27-wk membrane group exhibited significantly more (p = 0.004) connective tissue height than the control group or either of the 9-wk groups. The amount of regenerated alveolar bone was significantly greater for the 27-wk membrane group than for the control (p = 0.001) and 9-wk groups. Mean junctional epithelium measurements were significantly greater (p = 0.012) for the control. The use of a bioresorbable membrane enhances bone regeneration when a buccal defect exists at the time of periradicular surgery.