CEREBRAL VASOREACTIVITY IN UNILATERAL CAROTID-ARTERY DISEASE - A COMPARISON OF BLOOD-FLOW VELOCITY AND REGIONAL CEREBRAL BLOOD-FLOW MEASUREMENTS
CEREBRAL VASOREACTIVITY IN UNILATERAL CAROTID-ARTERY DISEASE - A COMPARISON OF BLOOD-FLOW VELOCITY AND REGIONAL CEREBRAL BLOOD-FLOW MEASUREMENTS
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DOI：
10.1161/01.str.25.3.621
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发表时间：
1994-03-01
期刊：
影响因子：
8.3
通讯作者：
BAKKE, SJ
中科院分区：
文献类型：
--
作者：
DAHL, A;RUSSELL, D;BAKKE, SJ
背景和目的通过评估脑血管反应性获得的血流动力学信息具有临床意义，并可能对闭塞性颈动脉疾病患者的预后具有重要意义。本研究的目的是比较经颅多普勒和局部脑血流研究的结果时，用于评估脑血管reactivity.Methods血流速度在大脑中动脉和局部脑血流在各自的灌注领域进行了比较，在52例严重的单侧颈动脉狭窄或闭塞。结果大脑中动脉血流速度增加的不对称性（正常侧与病变侧相比）明显大于脑血流增加的不对称性。显著相关（r= 0.63，P
Background and Purpose Hemodynamic information obtained by assessing cerebral vasoreactivity is of clinical interest and may have prognostic significance in patients with occlusive carotid disease. The aim of this study was to compare the results of transcranial Doppler and regional cerebral blood flow studies when used to assess cerebral vasoreactivity.Methods Blood flow velocities in both middle cerebral arteries and regional cerebral blood flow in their respective perfusion territories were compared in 52 patients with severe unilateral carotid stenosis or occlusion. The studies were first performed under basal conditions and repeated after the intravenous administration of Ig acetazolamide.Results Asymmetry (normal compared with pathological side) in middle cerebral artery blood velocity increase was significantly greater than the asymmetry in cerebral blood flow increase in the perfusion territories of the arteries. A significant correlation (r=.63, P