MiR398 and plant stress responses.
MiR398 and plant stress responses.
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DOI：
10.1111/j.1399-3054.2011.01477.x
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发表时间：
2011-09
影响因子：
6.4
通讯作者：
Cheng Zhu;Yanfei Ding;Haili Liu
中科院分区：
文献类型：
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作者：
Cheng Zhu;Yanfei Ding;Haili Liu
由于其固着的性质，植物不断地暴露于众多的非生物和生物胁迫。植物复杂的胁迫反应机制的研究取得了很大进展。MicroRNAs（miRNAs）是近年来发现的在转录后水平调控基因表达的重要分子，参与植物逆境胁迫应答。大多数植物miRNA通常介导其靶mRNA的切割。一些miRNAs在胁迫下表达上调或下调的现象表明miRNAs在植物对非生物和生物胁迫的抗性中起着重要作用。操纵miRNA引导的基因调控可能代表了一种新的方式来工程植物，提高胁迫耐受性。在胁迫响应的miRNAs中，miRNA398（miR398）被认为是与植物胁迫调节网络直接相关的miRNAs，并且调节植物对氧化胁迫、水分亏缺、盐胁迫、脱落酸胁迫、紫外线胁迫、铜和磷酸盐缺乏、高蔗糖和细菌感染的响应。本文综述了miR398在植物逆境响应中的重要作用，并对以miR398为中心的基因调控网络进行了讨论。
Because of their sessile nature, plants are constantly exposed to a multitude of abiotic and biotic stresses. Great progress has been made in elucidating the complex stress response mechanisms in plants. MicroRNAs (miRNAs), recently recognized as important regulators of gene expression at the posttranscriptional level, have been found to be involved in plant stress responses. Most plant miRNAs usually mediate cleavage of their target mRNAs. The observation that some miRNAs are up- or downregulated in response to stress implies that miRNAs play vital roles in plant resistance to abiotic and biotic stresses. Manipulation of miRNA-guided gene regulation may represent a new way to engineer plants with improved stress tolerance. Among stress-responsive miRNAs, miRNA398 (miR398) is a miRNA proposed to be directly linked to the plant stress regulatory network and regulates plant responses to oxidative stress, water deficit, salt stress, abscisic acid stress, ultraviolet stress, copper and phosphate deficiency, high sucrose and bacterial infection. This review highlights recent progress in understanding the crucial role of miR398 in plant stress responses, and also includes a discussion of miR398-centered gene regulatory network.