STUDIES IN MULTIPLE SCLEROSIS: VII. SIMILARITIES BETWEEN SOME FORMS OF ENCEPHALOMYELITIS AND MULTIPLE SCLEROSIS
STUDIES IN MULTIPLE SCLEROSIS: VII. SIMILARITIES BETWEEN SOME FORMS OF ENCEPHALOMYELITIS AND MULTIPLE SCLEROSIS
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多发性硬化症的研究：VII。
DOI：
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发表时间：
1936
期刊：
影响因子：
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通讯作者：
T. J. Putnam
中科院分区：
文献类型：
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作者：
T. J. Putnam
认为多发性硬化症是一种在急性期被认为是某些类型的急性“脊髓炎”或“脑脊髓炎”的过程的晚期的建议可以追溯到上个世纪。[1]争论的焦点已经有所改变，现在的焦点不是多发性硬化症的病变是否是进展性的--这似乎是几乎普遍接受的--而是更具体的一点，即在“脱髓鞘性脑脊髓炎”组中观察到的播散性变性灶是否是进展性的。或脑脊髓病，最明确的表现为接种后和麻疹后形式，代表典型的硬化斑的急性形式。这个问题本身就是一个难题，因为它包括试图将急性病变与慢性病变进行比较。由于同一种疾病的每一个病例中常常可以观察到几种不同的病变，这就增加了困难。
The suggestion that multiple sclerosis represents a late stage of a process which is recognized in its acute stage as acute "myelitis" or "encephalomyelitis" of certain types dates well back into the last century. 1 The scene of battle has changed somewhat and now centers less about the question whether the lesions of multiple sclerosis are progressive—it appears to be almost universally accepted that they are-than about the more specific point as to whether the disseminated foci of degeneration seen in the group of "demyelinating encephalomyelitides" or encephalomyelopathies most definitely represented by the postvaccinal and postmeasles forms represent an acute form of typical sclerotic plaques. The issue is a difficult one in itself, for it consists in attempting to compare an acute lesion with a chronic one. This difficulty is increased by the fact that several varieties of lesions may often be observed in each case of the same disease.