RE-AIMing research for application: Ways to improve evidence for family medicine
RE-AIMing research for application: Ways to improve evidence for family medicine
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DOI：
10.3122/jabfm.19.1.11
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发表时间：
2006-01-01
影响因子：
2.9
通讯作者：
Glasgow, Russell E.
中科院分区：
文献类型：
--
作者：
Glasgow, Russell E.
目的：概述临床研究设计和测量方面的变化，以提高研究与家庭医学的相关性。方法：回顾传统的疗效研究范式，并讨论为什么需要扩大这一范式。提出了实用的临床和行为试验框架，以及用于规划、评估和报告研究的RE-AIM模型。结果：为提高研究的外部有效性和与家庭医学的相关性，建议的改变包括研究多种临床实践、现实的替代方案选择、异质性和代表性的患者，以及包括成本、患者和工作人员的行为变化、泛化和生活质量在内的多种结果。结论：所讨论的方法和程序可以帮助项目规划者、评估者和研究文章的读者评估可重复性、效果的一致性和广泛采用干预措施的可能性。
Objective: To outline changes in clinical research design and measurement that should enhance the relevance of research to family medicine.Methods: Review of the traditional efficacy research paradigm and discussion of why this needs to be expanded. Presentation of practical clinical and behavioral trials frameworks, and of the RE-AIM model for planning, evaluating, and reporting studies.Results: Recommended changes to improve the external validity and relevance of research to family medicine include studying multiple clinical practices, realistic alternative program choices, heterogeneous and representative patients, and multiple outcomes including cost, behavior change of patients and staff, generalization, and quality of life.Conclusions: The methods and procedures discussed can help program planners, evaluators and readers of research articles to evaluate the replicability, consistency of effects, and likelihood of widespread adoption of interventions.