INDOOR AIR-POLLUTION AND ASTHMA IN HOSPITALIZED CHILDREN IN A TROPICAL ENVIRONMENT
INDOOR AIR-POLLUTION AND ASTHMA IN HOSPITALIZED CHILDREN IN A TROPICAL ENVIRONMENT
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DOI：
10.3109/02770909409077752
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发表时间：
1995-01-01
影响因子：
1.9
通讯作者：
KASIM, MS
中科院分区：
文献类型：
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作者：
AZIZI, BHO;ZULKIFLI, HI;KASIM, MS
我们进行了一项以医院为基础的研究，以检验室内空气污染与居住在吉隆坡市的幼儿急性哮喘相关的假设。共招募了158名1个月至5岁的首次因哮喘住院的儿童作为病例。对照组为201名同龄儿童，他们因呼吸系统疾病以外的原因住院。信息是从母亲使用标准化问卷。单因素分析确定了两个室内污染变量为显着因素。与成年吸烟者共用一间卧室以及每周至少三个晚上暴露在蚊香烟雾中都与哮喘风险增加有关。Logistic回归分析证实，与成年吸烟者同住（OR = 1.91，95% CI 1.13，3.21）和接触蚊香烟雾（OR = 1.73，95% CI 1.02，2.93）是独立的危险因素。与急性哮喘独立相关的其他因素包括既往过敏史、一级亲属哮喘史、低出生体重和咳嗽兄弟姐妹。哮喘与接触煤油炉、柴炉、喷雾驱蚊剂、住房类型或拥挤之间没有关联。我们的结论是，室内空气污染是一个可以避免的因素，在热带环境中的儿童哮喘发病率增加。
We performed a hospital-based study to examine a hypothesis that indoor air pollution was associated with acute asthma in young children living in Kuala Lumpur City. A total of 158 children aged 1 month to 5 years hospitalized for the first time for asthma were recruited as cases. Controls were 201 children of the same age group who were hospitalized for causes other than a respiratory illness. Information was obtained from mothers using a standardized questionnaire. Univariate analysis identified two indoor pollution variables as significant factors. Sharing a bedroom with an adult smoker and exposure to mosquito coil smoke at least three nights in a week were both associated with increased risk for asthma. Logistic regression analysis confirmed that sharing a bedroom with an adult smoker (OR = 1.91, 95% CI 1.13, 3.21) and exposure to mosquito coil smoke (OR = 1.73, 95% CI 1.02, 2.93) were independent risk factors. Other factors independently associated with acute asthma were previous history of allergy, history of asthma in first-degree relatives, low birth weight, and the presence of a coughing sibling. There was no association between asthma and exposure to kerosene stove, wood stove, aerosol mosquito repellent, type of housing, or crowding. We conclude that indoor air pollution is an avoidable factor in the increasing morbidity due to asthma in children in a tropical environment.