Conjugated bile acids and intestinal flora during the preruminant stage in goat. Influence of a lamb milk replacer

Conjugated bile acids and intestinal flora during the preruminant stage in goat. Influence of a lamb milk replacer
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DOI:
10.1076/apab.104.2.246.12884
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发表时间:
1996-01-01
影响因子:
3
通讯作者:
MartinezVictoria, E
MartinezVictoria, E
中科院分区:
医学4区
文献类型:
--
作者:
Rueda, A;Manas, M;MartinezVictoria, E

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用羊奶或代奶喂养45只泌乳仔猪,比较出生后第一个月内牛磺酸和甘氨酸共轭胆汁酸的演变和肠道菌群的演变。分别取1、7、14、21和28日龄儿童的肝胆汁样本,用高效液相色谱法测定共轭胆汁酸。测定14日龄和28日龄动物的细菌菌群。结果表明,在本实验条件下,牛磺酸偶联胆汁酸明显优于甘氨酸偶联胆汁酸。这种优先的牛头结合模式在所有测试年龄和两组研究中都持续存在。另一方面,在乳化剂的加工过程中所使用的蛋白质和脂肪的质量似乎会影响肠道菌群和共轭胆汁酸的出生后进化。
A total of 45 preruminant gents were fed either goat milk or a milk substitute to compare the evolution of taurine and glycine conjugated bile acids and the evolution of the intestinal flora during the first month of life. Samples of hepatic bile were obtained from kids of 1, 7, 14, 21, and 28 days old and conjugated bile acids were measured by high performance liquid chromatography. Bacterial flora were determined in 14 and 28 day old animals. Ours results show that under our experimental conditions tauraconjugated bile acids clearly predominated over the conjugated with glycine. This pattern of preferential tauroconjugation persisted at all ages tested and in both groups studied. On the other hand, it seems that the quality of the protein and fat used in the elaboration of the milk replacer effects the intestinal flora: and the postnatal evolution of conjugated bile acids.