Wire electrodes for chronic single unit recording of dopamine cells in substantia nigra pars compacta of awake rats.
Wire electrodes for chronic single unit recording of dopamine cells in substantia nigra pars compacta of awake rats.
复制标题
用于慢性单单位记录清醒大鼠黑质致密部多巴胺细胞的线电极。
DOI：
10.1016/0165-0270(87)90103-8
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发表时间：
1987
影响因子：
3
通讯作者：
Freed,CR
中科院分区：
文献类型：
--
作者：
Diana,M;Garcia-Munoz,M;Freed,CR
研究人员测试了不同尺寸的不锈钢丝电极，并涂上了不同的绝缘材料，目的是找到一种柔韧的细丝，可以在不受约束的清醒大鼠的大脑深层结构中记录小细胞。我们的主要兴趣是在运动过程中记录黑质致密部的细胞。我们发现，用漆和聚二甲苯C双重绝缘的应力释放18 μm不锈钢丝提供了在激烈的电机行为下记录单个单元所需的阻抗、物理尺寸和灵活性。
Stainless steel wire electrodes of varying sizes and coated with different insulating materials were tested in order to find a flexible fine wire which would allow the recording of small cells in deep structures of the brain in unrestrained, awake rats. Our main interest is to record from cells of substantia nigra pars compacta during locomotion. We found that stress relieved 18 μm stainless steel wire doubly insulated with lacquer and Parylene C provided the impedance, physical size, and flexibility needed to record single units during intense motor behavior.