SYNTHESIS OF ISOCOUMARIN COMPOUNDS, 8-HYDROXY-6-METHOXY-3-PENTYL-1H-ISOCHROMEN-1-ONE AND FUSARIUMIN ANALOG USING PALLADIUM-CATALYZED CARBONYLATION TRAPPING WITH O-ENOLATE
SYNTHESIS OF ISOCOUMARIN COMPOUNDS, 8-HYDROXY-6-METHOXY-3-PENTYL-1H-ISOCHROMEN-1-ONE AND FUSARIUMIN ANALOG USING PALLADIUM-CATALYZED CARBONYLATION TRAPPING WITH O-ENOLATE
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DOI：
10.3987/com-17-13746
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发表时间：
2017-08-01
期刊：
影响因子：
0.6
通讯作者：
Makabe, Hidefumi
中科院分区：
文献类型：
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作者：
Asai, Masaki;Hattori, Yasunao;Makabe, Hidefumi
采用邻烯醇钯催化的羰基化捕集方法，合成了6，8-二烷氧基异香豆素骨架。将该方法应用于从密花苔草及其类似物中分离的8-hydroxy-6-methoxy-3-penty1-1H-isochromen-1-one的合成。
Concise synthesis of 6,8-dialkoxyisocoumarin framework was achieved using Pd-catalyzed carbonylation trapping with O-enolate. This methodology was applied to the synthesis of 8-hydroxy-6-methoxy-3-penty1-1H-isochromen-1-one isolated from Tessmannia densiflora and fusariumin analog.