Palladium-Catalyzed Intermolecular Aminocarbonylation of Alkenes: Efficient Access of β-Amino Acid Derivatives
Palladium-Catalyzed Intermolecular Aminocarbonylation of Alkenes: Efficient Access of β-Amino Acid Derivatives
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DOI：
10.1021/jacs.5b00719
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发表时间：
2015-02-25
影响因子：
15
通讯作者：
Liu, Guosheng
中科院分区：
文献类型：
--
作者：
Cheng, Jiashun;Qi, Xiaoxu;Liu, Guosheng
本文报道了一种新的钯催化烯烃分子间氨基羰基化反应，其中高价碘试剂的使用可以加速分子间氨基钯化反应，从而提供成功的催化转化。目前的转化是从简单烯烃生成β-氨基酸衍生物的最方便的方法之一。
A novel palladium-catalyzed intermolecular aminocarbonylation of alkenes has been developed in which the employment of hypervalent iodine reagent can accelerate the intermolecular aminopalladation, which thus provides the successful catalytic transformation. The current transformation presents one of the most convenient methods to generate beta-amino acid derivatives from simple alkenes.