Vertically Aligned Gold Nanorod Monolayer on Arbitrary Substrates: Self-Assembly and Femtomolar Detection of Food Contaminants
Vertically Aligned Gold Nanorod Monolayer on Arbitrary Substrates: Self-Assembly and Femtomolar Detection of Food Contaminants
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DOI：
10.1021/nn401685p
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发表时间：
2013-07-01
期刊：
影响因子：
17.1
通讯作者：
Xiong, Qihua
中科院分区：
文献类型：
--
作者：
Peng, Bo;Li, Guangyuan;Xiong, Qihua
公众对食品丑闻的关注迫切需要开发有效且可靠的方法来检测食品污染物。目前流行的检测主要基于液相色谱、质谱或比色法，这些方法通常需要复杂且耗时的步骤或样品制备。在此，我们开发了一种简单的策略来组装具有标称间隙距离 0.8 nm 的垂直排列单层金纳米棒，并展示了它们在通过表面增强拉曼散射光谱 (SERS) 快速检测飞摩尔水平的增塑剂和三聚氰胺污染方面的应用。橙汁中增塑剂的 SERS 信号对于浓度低至 0.9 fM 的浓度非常敏感。这是迄今为止报道的最低检测限，比美国标准（6 ppb）低7个数量级。高度组织的垂直阵列产生可重复的“SERS活性位点”，并且可以在任意基板上实现，从硅、氮化镓、玻璃到柔性聚萘二甲酸乙二醇酯基板。
Public attention to the food scandals raises an urgent need to develop effective and reliable methods to detect food contaminants. The current prevailing detections are primarily based upon liquid chromatography, mass spectroscopy, or colorimetric methods, which usually require sophisticated and time-consuming steps or sample preparation. Herein, we develop a facile strategy to assemble the vertically aligned monolayer of Au nanorods with a nominal 0.8 nm gap distance and demonstrate their applications in the rapid detection of plasticizers and melamine contamination at femtomolar level by surface-enhanced Raman scattering spectroscopy (SERS). The SERS signals of plasticizers are sensitive down to 0.9 fM concentrations in orange juices. It is the lowest detection limit reported to date, which is 7 orders of magnitude lower than the standard of United States (6 ppb). The highly organized vertical arrays generate the reproducible "SERS-active sites" and can be achieved on arbitrary substrates, ranging from silicon, gallium nitride, glass to flexible poly(ethylene naphthalate) substrates.