Microscale and Nanoscale Electrophotonic Diagnostic Devices.
Microscale and Nanoscale Electrophotonic Diagnostic Devices.
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DOI：
10.1101/cshperspect.a034249
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发表时间：
2019-05-01
影响因子：
5.4
通讯作者：
Bohn PW
中科院分区：
文献类型：
--
作者：
Fu K;Xu W;Hu J;Lopez A;Bohn PW
在复杂环境中检测和识别感染原和潜在病原体并确定其作用方式是一项迫切需要。传统诊断针对单一特征，如光谱响应、表面受体、质量、固有电导率等。然而，检测技术的进步已经确定了多种作用模式相结合以获得增强性能特征的新方法。在这方面特别吸引人的是，能够将光耦合到电子易位的电泳设备最近经历了快速增长，并为诊断提供了显着优势。在本章中，我们探讨了三种结合电子学和光子学的具体有前途的方法：(a)基于闭合双极电化学耦合电子转移到颜色或荧光的分析；(b)基于局部表面等离子体共振的传感器；(c)新兴的纳米光子学方法，如基于零模波导和超材料的方法。
Detecting and identifying infectious agents and potential pathogens in complex environments and characterizing their mode of action is a critical need. Traditional diagnostics have targeted a single characteristic, e.g. spectral response, surface receptor, mass, intrinsic conductivity, etc. However, advances in detection technologies have identified emerging approaches in which multiple modes of action are combined to obtain enhanced performance characteristics. Particularly appealing in this regard, electrophotonic devices capable of coupling light to electron translocation have experienced rapid recent growth and offer significant advantages for diagnostics. In this chapter, we explore three specific promising approaches that combine electronics and photonics: (a) assays based on closed bipolar electrochemistry coupling electron transfer to color or fluorescence (b) sensors based on localized surface plasmon resonances, and (c) emerging nanophotonics approaches, such as those based on zero-mode waveguides and metamaterials.
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影响因子：
7.4
作者：
Byers, Joshua C.;Nadappuram, Binoy Paulose;Unwin, Patrick R.
通讯作者：
Unwin, Patrick R.
影响因子：
7.4
作者：
Bundy, J;Fenselau, C
通讯作者：
Fenselau, C
影响因子：
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Crooks, Richard M.
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影响因子：
3.7
作者：
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通讯作者：
Van Duyne, Richard P.
影响因子：
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作者：
Guerrette, Joshua P.;Oja, Stephen M.;Zhang, Bo
通讯作者：
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