Phasor representation of oxy- and deoxyhemoglobin concentrations: what is the meaning of out-of-phase oscillations as measured by near-infrared spectroscopy?
Phasor representation of oxy- and deoxyhemoglobin concentrations: what is the meaning of out-of-phase oscillations as measured by near-infrared spectroscopy?
复制标题
氧合血红蛋白和脱氧血红蛋白浓度的相量表示：近红外光谱测量的异相振荡的含义是什么？
DOI：
10.1117/1.3483466
复制
发表时间：
2010
影响因子：
3.5
通讯作者：
Fantini,Sergio
中科院分区：
文献类型：
--
作者：
Zheng,Feng;Sassaroli,Angelo;Fantini,Sergio
我们提出了一个相量表示的振荡在一个给定的频率（或相对较窄的频带）的血红蛋白浓度在组织中，以及血红蛋白浓度测量的近红外光谱。该表示提供了氧合、脱氧和总血红蛋白浓度（分别为[HbO]、[Hb]和[HbT]）振荡之间的相位关系的直观可视化。我们观察到，测得的振荡[Hb]和[HbO]的相位差既不是0也不是必须从不同的生理过程，是相位（或时移）相对于彼此的组合的结果。最后，我们提出了使用互相关相量映射的相位关系和相关水平在空间上不同的位置在一个给定的频率测量的血红蛋白振荡。这种表示可能会在大脑功能连接网络的研究中找到自然的应用。
We propose a phasor representation for oscillations at a given frequency (or relatively narrow frequency band) of hemoglobin concentrations in tissue, as well as hemoglobin concentrations measured by near-infrared spectroscopy. This representation provides a straightforward visualization of the phase relationships between oscillations of oxy-, deoxy-, and total hemoglobin concentrations ([HbO], [Hb], and [HbT], respectively). We observe that measured oscillations of [Hb] and [HbO] with a phase difference that is neither 0 normust result from the combination of different physiological processes that are out of phase (or time shifted) with respect to each other. Finally, we propose the use of cross-correlation phasors to map phase relationships and correlation levels among hemoglobin oscillations measured at spatially distinct locations at a given frequency. Such a representation may find a natural application in the study of functional connectivity networks in the brain.