Locus- and population-specific selection and differentiation between incipient species of Anopheles gambiae.
Locus- and population-specific selection and differentiation between incipient species of Anopheles gambiae.
复制标题
冈比亚按蚊早期物种之间的位点和群体特异性选择和分化。
DOI：
10.1093/molbev/msm143
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发表时间：
2007
影响因子：
10.7
通讯作者：
Hahn,MatthewW
中科院分区：
文献类型：
--
作者：
Turner,ThomasL;Hahn,MatthewW
冈比亚按蚊是撒哈拉以南非洲疟疾的主要传播媒介，它分为两个同域初生种，即Mform和Sform。最近对每种形式的基因组分析表明，形式之间的分化聚集在基因组的3个互不相连的区域。在这里，我们将这些“物种形成的基因组岛”的研究扩展到多个种群，包括其中一个岛上的所有基因。其中两个岛上的曼氏变型在所有种群的所有个体之间完成了分化，证实了曼氏变型是生殖隔离的类群。第三个岛(位于染色体2R上)的分化仅限于喀麦隆人群。喀麦隆在这个位置的变异减少，与阿拉伯按蚊群体的分歧增加，这支持了适应与生殖隔离的联系。
Anopheles gambiae, the primary mosquito vector of malaria in sub-Saharan Africa, is divided into 2 sympatric incipient species known asMform andSform. Recent genomic analysis of each form revealed that differentiation between forms is clustered into 3 unlinked regions of the genome. Here, we expand the investigation of these “genomic islands of speciation” to multiple populations, including all of the genes across one of the islands. Differentiation between theMandSforms in 2 of the islands is complete across all individuals in all populations, confirming that theMandSforms are reproductively isolated taxa. Differentiation at the third island (on chromosome 2R) is limited to Cameroon populations. There is reduced variation in theMform in Cameroon at this location and increased divergence to the outgroupAnopheles arabiensis, supporting an association of adaptation with reproductive isolation.