Renal mechanoreceptors in nonhuman primates.
Renal mechanoreceptors in nonhuman primates.
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非人类灵长类动物的肾机械感受器。
DOI：
10.1152/ajpregu.1985.248.2.r202
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Tomomatsu,E
中科院分区：
文献类型：
--
作者：
Gilmore,JP;Tomomatsu,E
本实验首次描述了非人灵长类动物肾脏机械敏感性受体的传入放电特征。获得了27个具有机械敏感性受体活性的单单位。在自主呼吸下，传入放电发生规律性（脉冲同步）或不规律性（脉冲异步）。部分阻断肾静脉和升高动脉压可增加脉搏同步单位的活动。出血或肾动脉闭塞时，冲动活动减少或消失。部分阻断肾静脉可增加脉搏非同步单位的冲动活动。安静单位的冲动活动仅由肾静脉的部分闭塞引起。输尿管压力的增加（50 mmHg）产生了增加或诱导的冲动活动，只有三个测试的27个纤维。肾脏受压或肾静脉闭塞与体循环动脉压降低相关，而肾动脉闭塞则导致体循环动脉压升高。输尿管压力升高（50 mmHg）不会引起动脉压变化。
The present experiments provide the first description of the afferent discharge characteristics of renal mechanosensitive receptors in the nonhuman primate. Twenty-seven single units with mechano-sensitive receptor activity were obtained. Afferent discharge occurred regularly (pulse synchronous) or irregularly (pulse asynchronous) under spontaneous respiration. The activity of pulse synchronous units was increased by partial occlusion of the renal vein and elevation of arterial pressure. Impulse activity decreased or disappeared during bleeding or renal arterial occlusion. The impulse activity of pulse asynchronous units was increased by partial occlusion of the renal vein. The impulse activity of silent units was induced only by partial occlusion of the renal vein. An increase in ureteral pressure (50 mmHg) produced an increase or induced impulse activity in only three of the 27 fibers tested. Compression of the kidney or renal venous occlusion was associated with a decrease in systemic arterial pressure, whereas renal arterial occlusion produced a rise in systemic arterial pressure. An increase in ureteral pressure (50 mmHg) did not produce a change in arterial pressure.