Comparison of the Xpert Methicillin-Resistant Staphylococcus aureus (MRSA) Assay, BD GeneOhm MRSA Assay, and Culture for Detection of Nasal and Cutaneous Groin Colonization by MRSA

Comparison of the Xpert Methicillin-Resistant Staphylococcus aureus (MRSA) Assay, BD GeneOhm MRSA Assay, and Culture for Detection of Nasal and Cutaneous Groin Colonization by MRSA
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Xpert 耐甲氧西林金黄色葡萄球菌 (MRSA) 检测、BD GeneOhm MRSA 检测以及培养物检测鼻腔和皮肤腹股沟 MRSA 定植的比较

DOI:
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发表时间:
2009
影响因子:
9.4
通讯作者:
M. Grayson
M. Grayson
中科院分区:
医学2区
文献类型:
--
作者:
P. Kelley;E. Grabsch;B. Howden;Wei Gao;M. Grayson

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在两种商业PCR检测试剂盒(Xpert MRSA检测试剂盒和BD GeneOhm MRSA检测试剂盒)中,使用鼻拭子和腹股沟拭子联合检测耐甲氧西林金黄色葡萄球菌定植。与常规培养相比,两者的敏感性(分别为87.0%和84.8%)和特异性(分别为93.8%和92.7%)相似。联合PCR检测提供了一个快速和更完整的评估殖民的成本类似于单一网站的分析。
ABSTRACT Detection of methicillin (meticillin)-resistant Staphylococcus aureus colonization was assessed using combined nose and groin swabs in two commercial PCR assays (the Xpert MRSA assay and the BD GeneOhm MRSA assay). Compared to routine culture, both had similar sensitivities (87.0% versus 84.8%, respectively) and specificities (93.8% versus 92.7%, respectively). Combined PCR assays provide a rapid and more-complete assessment of colonization at a cost similar to that of single-site analysis.