Comparison of Quality of Life After Transnasal Endoscopic vs Open Skull Base Tumor Resection
Comparison of Quality of Life After Transnasal Endoscopic vs Open Skull Base Tumor Resection
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DOI：
10.1001/archoto.2011.1146
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发表时间：
2012-02-01
影响因子：
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通讯作者：
Gil, Ziv
中科院分区：
文献类型：
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作者：
Abergel, Avraham;Cavel, Oren;Gil, Ziv
目的：评价同一团队开腹和内窥镜下颅底手术对患者生活质量的影响。设计：回顾性调查。地点：大学附属医学中心。患者：78例患者，经扩大内窥镜(n=41)或颅下入路(n=37)行颅底肿瘤切除术。主要观察指标：采用多维、疾病特异性问卷，共36个条目。评估生活质量的六个相关领域：表现的角色、身体功能、活力、疼痛、特定症状和对情绪的影响。结果：两组在临床和人口统计学方面没有显著差异(P>；.06)。单因素和多因素分析显示，接受内窥镜手术的患者在躯体功能和情绪影响两个领域的得分显著高于接受颅下手术的患者(P
Objective: To evaluate the impact of the open and endoscopic skull base surgery performed by the same team on patients' quality of life.Design: Retrospective survey.Setting: University-affiliated medical center.Patients: The study included 78 patients who underwent surgery for removal of skull base neoplasms through an expanded endoscopic( n=41) orasubcranial (n=37) approach.Main Outcome Measure: A multidimensional, disease-specific questionnaire with 36 items was used. Six relevant domains of QOL were assessed: role of performance, physical functioning, vitality, pain, specific symptoms, and impact on emotions.Results: There were no significant clinical or demographic differences between the 2 study groups (P>.06). Univariate and multivariate analyses showed that patients who underwent endoscopic surgery reported significantly better scores in the physical function and impact on emotions domains than the patients who underwent subcranial surgery (P