Development of NADPH diaphorase-positive pedunculopontine nucleus neurons.
Development of NADPH diaphorase-positive pedunculopontine nucleus neurons.
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NADPH 心肌黄酶阳性桥脚核神经元的发育。
DOI：
10.1016/0014-4886(89)90003-4
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发表时间：
1989
影响因子：
5.3
通讯作者：
Garcia-Rill,E
中科院分区：
文献类型：
--
作者：
Skinner,RD;Conrad,C;Henderson,V;Gilmore,SA;Garcia-Rill,E
用烟酰胺腺嘌呤二核苷酸磷酸(NADPH)黄递酶组织化学方法对新生和成年大鼠桥脑脚核内胆碱能神经元进行定位。对细胞体面积的测量显示，出生时平均面积约为200μm2，随后在2周龄时显著增加至约500μm2。此后，细胞面积减少，到5周龄时，神经元已达到约300μm2的成体大小。在2周龄结束时，细胞大小的显著增加与运动和其他节律功能控制系统的发育中的重大事件有关。
Nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemistry was used to localize cholinergic neurons in the pedunculopontine nucleus of neonatal and adult rats. Measurements of cell body areas revealed an average area around 200 μm2at birth, followed by a significant increase to approximately 500 μm2by 2 weeks of age. Thereafter, there was a decrease in cell area such that by 5 weeks of age the neurons had attained their adult size of around 300 μm2. The marked increase in cell size at the end of 2 weeks of age is discussed in relation to significant events in the development of locomotor and other rhythmic function control systems.