Cardiac mechanosensitivity and stretch-activated ion channels
Cardiac mechanosensitivity and stretch-activated ion channels
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DOI:
10.1016/s1050-1738(96)00119-3
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发表时间:
1997-01-01
影响因子:
9.3
通讯作者:
Sachs, F
中科院分区:
文献类型:
--
作者:
Bett, GCL;Sachs, F
Mechanosensitivity is a ubiquitous property of cells, and mechanosensitive ion channels (MSCs) are hypothesized to be the transducers. In the heart MSCs are likely to account for changes in beating rate as a function of filling and for initiating stretch-induced arrhythmias (for example, following a myocardial infarction). Pharmacological agents that affect MSCs may provide a new class of antiarrhythmic drugs. (C) 1997, Elsevier Science Inc.