Life-history correlates of steroid concentrations in wild peripartum baboons
Life-history correlates of steroid concentrations in wild peripartum baboons
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DOI：
10.1002/ajp.20064
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发表时间：
2004-09-01
影响因子：
2.4
通讯作者：
Gesquiere, LR
中科院分区：
文献类型：
--
作者：
Altmann, J;Lynch, JW;Gesquiere, LR
妊娠晚期和哺乳期早期的类固醇浓度可能受到雌性生殖史和当前状况的影响，并可能反过来预测随后的生活史事件，如后代的存活率。本研究通过对围产期狒狒（Papio cynocephalus）重复取样的粪便类固醇分析，在野生灵长类动物种群中调查了这些关系。在Amboseli盆地内采集5组32只母鼠产前8周和产后13周的粪便样本。从1999年12月到2002年2月，从39个围产期的个体中收集了176份粪便样本。用放射免疫法测定粪便中孕激素（fP）、雌激素代谢物（fE）、糖皮质激素（fGC）和睾酮代谢物（fT）的浓度。从妊娠晚期到哺乳期，类固醇浓度下降，fE和m的下降幅度最大，也最陡峭。初产母鼠在妊娠最后2个月的平均fE浓度明显高于多产母鼠。在多胎女性中，怀孕后期携带男性胎儿的女性的fE和fT明显高于携带女性胎儿的女性。在哺乳期早期，年轻母亲的高血氧饱和度预示着婴儿在出生后第一年的死亡。这些发现说明了重复粪便类固醇取样在阐明自然种群生活史变异机制方面的潜在力量。他们还记录了亚组之间激素谱的显著差异，并强调这些规范的亚组信息对于解释激素-行为关联的个体差异至关重要。
Steroid concentrations during late pregnancy and early lactation may be affected by both a female's reproductive history and her current condition, and may in turn predict subsequent life-history events, such as offspring survival. This study investigated these relationships in a wild primate population through the use of fecal steroid analysis in repeated sampling of peripartum baboons (Papio cynocephalus). Fecal samples were collected from 32 females in five groups within the Amboseli basin during 8 weeks prior to parturition and 13 weeks postpartum. From December 1999 through February 2002, 176 fecal samples were collected from individuals representing 39 peripartum periods. Fecal concentrations of progestins (fP), estrogen metabolites (fE), glucocorticoids (fGC), and testosterone metabolites (fT) were measured by radioimmunoassay. Steroid concentrations declined from late pregnancy to lactation, and the decline was greatest and most precipitous for fE and M. Primiparous females had significantly higher mean fE concentrations in each of the last 2 months of pregnancy compared to multiparous females. Among multiparous females, fE and fT were significantly higher during late pregnancy in females carrying a male fetus compared to those carrying a female fetus. During early lactation, high fT in young mothers predicted subsequent infant death during the first year of life. These findings illustrate the potential power of repeated fecal-steroid sampling to elucidate mechanisms of life-history variability in natural populations. They also document significant differences in hormone profiles among subgroups, and highlight that such normative subgroup information is essential for interpreting individual variability in hormone-behavior associations.