COMPUTER MODELING OF BIOPROSTHETIC HEART-VALVES
COMPUTER MODELING OF BIOPROSTHETIC HEART-VALVES
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DOI：
10.1016/1010-7940(92)90031-r
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发表时间：
1992-01-01
影响因子：
3.4
通讯作者：
CHRISTIE, GW
中科院分区：
文献类型：
--
作者：
CHRISTIE, GW
基于计算机的组织心脏瓣膜模型的基本假设和原则进行了说明。该模型用于将瓣叶形态的观察结果与适当瓣膜功能的要求联系起来。应力是限制人工生物心脏瓣膜寿命的基本机械因素-瓣叶中的应力水平越高，瓣叶能够保持令人满意的结构完整性的时间越短。直接测量真实的心脏瓣膜的应力是不切实际的，但是计算应力并研究其与组织瓣膜设计的其他关键参数的相互依赖性是一个很好的替代方案。本文讨论了心脏瓣膜的计算机建模方法，并举例说明了该技术。比较了心包瓣、同种异体主动脉瓣和猪生物瓣的模型。
The underlying assumptions and principles of a computer-based model for tissue heart valves are described. The model is used to relate observations of leaflet morphology to the requirements of proper valve function. Stress is the fundamental mechanical factor that limits the longevity of bioprosthetic heart valves - the higher the stress levels in the leaflets, the shorter will be the time over which the leaflets can maintain satisfactory structural integrity. Direct measurement of stress is impractical with real heart valves, but the calculation of stress and the study of its interdependence on other key parameters of tissue valve design is a good alternative. The methodology of computer modelling of heart valves is discussed and the technique is illustrated with some examples. Models of pericardial valves, the aortic allograft and porcine bioprostheses are compared.