Efficacy of different cerclage suture materials in reducing preterm birth

Efficacy of different cerclage suture materials in reducing preterm birth
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不同环扎缝合材料减少早产的效果

DOI:
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发表时间:
2020
影响因子:
1.8
通讯作者:
J. Hagan
J. Hagan
中科院分区:
医学4区
文献类型:
--
作者:
I. Stafford;R. Kopkin;A. Berra;P. Daigle;M. Bergeron;S. Karlin;K. Hodge;J. Hagan

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摘要 目的:比较单丝缝合线、聚酯编织线和5mm胶带缝合线在减少早产(PTB)方面的效果。研究设计:使用ICD-9/10代码对2011年1月1日至2016年12月31日期间在美国路易斯安那州新奥尔良图罗医院接受环扎术的女性进行识别。所有图表均经过人口统计和产科变量的审查,包括分娩时的胎龄 (GA)。结果:在 145 名接受环扎术的女性中,有 36 名因图表不完整而被排除,留下 109 名进行分析。使用单丝、编织或 5mm 胶带环扎的妇女在环扎或分娩时的孕龄没有显着差异(分别为 p = .936 和 p = .919),并且在使用不同环扎材料的组中,≥32、34 或 37 周分娩的比例也没有差异(分别为 p = .270、p = .275 和 p = .419)。接受 17-OHP 治疗的患者与未接受 17-OHP 治疗的患者在分娩时 GA 没有差异 (p = .362)。出生体重 (p = .938)、阿普加评分 (p = .477, p = .430) 或新生儿重症监护病房 (NICU) (p = .304) 等出生结果也没有差异。分析显示,各组之间的特征没有差异,包括 PTB 病史或切除指征(p = .371,p = .317)。结论:当比较用于指定环扎术的不同缝合材料时,我们发现妊娠延长没有差异。我们还发现各组之间的孕产妇感染率或不良新生儿结局没有差异。基本原理本研究旨在评估不同缝合材料在增加分娩胎龄和减少早产方面的功效。
Abstract Objective: To compare the efficacy of monofilament suture, braided polyester thread, and 5 mm tape suture in reducing preterm birth (PTB). Study design: Women who received a cerclage at Touro Infirmary, New Orleans, LA, USA, between 1 January, 2011 and 31 December, 2016 were identified using ICD-9/10 codes. All charts were reviewed for demographic and obstetrical variables including gestational age (GA) at delivery. Results: Of 145 women who received a cerclage, 36 were excluded due to incomplete charts leaving 109 for analysis. There was no significant difference in gestational age at cerclage placement or delivery among women with monofilament, braided, or 5 mm tape cerclages (p = .936 and p = .919, respectively) nor was there a difference in the proportion who delivered at ≥32, 34, or 37 weeks across groups with differing cerclage material (p = .270, p = .275, and p = .419, respectively). There was no difference in GA at delivery for patients who received 17-OHP compared to those who did not (p = .362). There were also no differences with respect to birth outcomes such as birthweight (p = .938), Apgar scores (p = .477, p = .430) or neonatal intensive care admission rates (NICU) (p = .304). Analysis revealed no difference in characteristics between groups including history of PTB or indication for removal (p = .371, p = .317). Conclusion: We found no difference in pregnancy prolongation when comparing different suture material used for indicated cerclages. We also found no differences with respect to rates of maternal infection or adverse neonatal outcomes among groups. Rationale This study was conducted to evaluate the efficacy of different suture materials in increasing gestational age at delivery and reducing preterm birth.