Stretch-induced increase in activation of skinned muscle fibres by calcium.
Stretch-induced increase in activation of skinned muscle fibres by calcium.
复制标题
拉伸引起的钙对皮肤肌纤维的激活增加。
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
M. Endo
中科院分区：
文献类型：
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作者：
M. Endo
众所周知，活横纹肌纤维的主动强直张力随着超过其松弛长度的纤维长度的增加而线性降低1，2，这已经被解释为2厚（含肌球蛋白）和薄（含肌动蛋白）细丝之间的相互作用位点数量减少。已证明去皮的鲑鱼3在高浓度的钙4下表现出类似的行为。但机械性能的检查，部分激活的皮肤肌纤维表明，等距张力增加的纤维长度超过其松弛长度，如果收缩是由低浓度的钙离子引起的。
IT is well known that the active tetanic tension of a living striated muscle fibre decreases linearly with increase of fibre length beyond its slack length1,2 and this has been explained2 by the decreased number of interacting sites between thick (myosin-containing) and thin (actin-containing) filaments. Skinned fibres3 have been shown to behave similarly at high concentrations of calcium4. But examination of the mechanical properties, of partially activated skinned muscle fibres showed that the isometric tension increased with the increase of fibre length beyond its slack length if contraction was induced by a low concentration of calcium ions.