Periodontitis and health-related quality of life in hemodialysis patients.
Periodontitis and health-related quality of life in hemodialysis patients.
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DOI：
10.1002/cre2.50
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发表时间：
2017-03
影响因子：
1.8
通讯作者：
Nakamura H
中科院分区：
文献类型：
--
作者：
Iwasaki M;Borgnakke WS;Awano S;Yoshida A;Hamasaki T;Teratani G;Kataoka S;Kakuta S;Soh I;Ansai T;Nakamura H
牙周炎是常见的透析患者。目前的横断面研究旨在探讨血液透析患者牙周炎与健康相关生活质量（HRQoL）之间的关系。2008年5月至7月在日本北九州市的一家医疗中心接受血液透析的188名齿状回患者的数据进行了分析，同时应用改良的疾病控制和预防中心/美国牙周病学会牙周炎病例定义将参与者分为以下三组：重度，中度和无/轻度牙周炎。通过医学结局研究36项健康调查简表（SF-36）评估HRQoL，其中评分越高表示健康状况越好。使用一般线性模型评估牙周炎组与SF-36的8个健康领域之间的关联，该模型调整了年龄，性别，透析的根本原因，透析持续时间，合并症，血清生物标志物，体重指数，吸烟状况和饮酒。在188名参与者中，18名（9.6%）患有重度牙周炎，100名（53.2%）患有中度牙周炎，其余70名（37.2%）没有/轻度牙周炎。与无/轻度牙周炎的参与者相比，重度牙周炎的参与者在以下5个SF-36健康量表中的得分更差：身体功能，身体角色，活力，社会功能和心理健康（P < 0.05）。研究结果表明，透析患者中严重牙周炎和HRQoL下降之间存在独立关系。
Periodontitis is common among dialysis patients. The current cross‐sectional study aimed to explore associations between periodontitis and health‐related quality of life (HRQoL) among hemodialysis patients. Data from 188 dentate patients undergoing hemodialysis between May and July 2008 at a medical center in Kitakyushu city, Japan, were analyzed while applying modified Centers for Disease Control and Prevention/American Academy of Periodontology periodontitis case definitions to categorize the participants into the following three groups: severe, moderate, and no/mild periodontitis, respectively. HRQoL was assessed by the Medical Outcomes Study 36‐Item Short Form Health Survey (SF‐36) where a higher score indicates better health status. Associations between periodontitis groups and the eight health domains of SF‐36 were evaluated using general linear models that were adjusted for age, sex, underlying cause of dialysis, duration of dialysis, comorbidities, serum biomarkers, body mass index, smoking status, and alcohol use. Among the 188 participants, 18 (9.6%) had severe periodontitis, 100 (53.2%) had moderate periodontitis, and the remaining 70 (37.2%) had no/mild periodontitis. Compared with the participants with no/mild periodontitis, those with severe periodontitis had worse scores in the following five of eight SF‐36 health scales: physical functioning, role physical, vitality, social functioning, and mental health (P < 0.05). The findings suggest an independent relationship between severe periodontitis and decreased HRQoL among dialysis patients.