Examination of the structure of psychopathology using latent class analysis.
Examination of the structure of psychopathology using latent class analysis.
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使用潜在类别分析检查精神病理学的结构。
DOI：
10.1016/j.comppsych.2011.05.008
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发表时间：
2012
影响因子：
7.3
通讯作者：
Lewinsohn,PeterM
中科院分区：
文献类型：
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作者：
Olino,ThomasM;Klein,DanielN;Farmer,RichardF;Seeley,JohnR;Lewinsohn,PeterM
最近几项运用因子分析方法的研究发现，精神病理学的结构反映了广泛的内化和外化维度，其中内化维度又进一步分为恐惧障碍和痛苦障碍。尽管这些以变量为中心的研究为精神病理学的结构提供了重要的见解，但它们提供了关于个体病例分类的有限信息。本研究通过对个体而非变量进行分类的潜在类分析，对俄勒冈州青少年抑郁项目参与者的终身内化和外化精神病理学模式进行了研究。4类解决方案最适合数据。最大的一类（62.5%）包括相对较少精神病理的个体；1类（16.4%）以内化障碍为主，1类（16.9%）以外化障碍为主；最后一类（4.2%）的特点是内化和外化障碍。使用精神病发病率、气质和精神病理学家庭聚集的数据进一步检验了课程的有效性。班级在积极、消极和去抑制气质指数上的差异与理论预测一致。精神病理学的家族聚集模式显示了不同疾病传播的相对特异性。总的来说，这些发现支持了内化和外化障碍维度模型研究的结论，并将其扩展到以人为中心的分类方法。
Several recent studies using factor analytic methods find that the structure of psychopathology reflects broad internalizing and externalizing dimensions, with the internalizing dimension being further divided into fear and distress disorders. Although these variable-centered studies have provided important insights into the structure of psychopathology, they provide limited information about the classification of individual cases. The present study examines patterns of lifetime internalizing and externalizing psychopathology in participants from the Oregon Adolescent Depression Project using latent class analysis that classifies individuals rather than variables. A 4-class solution best fits the data. The largest class (62.5%) included individuals with relatively little psychopathology; 1 class (16.4%) was largely characterized by internalizing disorders, 1 class (16.9%), largely characterized by externalizing disorders; and the final class (4.2%), characterized by both internalizing and externalizing disorders. The validity of the classes was further examined using data on psychiatric morbidity, temperament, and family aggregation of psychopathology. Classes differed on indices of positive, negative, and disinhibited temperament in ways that were consistent with theoretical predictions. Patterns of familial aggregation of psychopathology demonstrated relative specificity of transmission of different disorders. Overall, the findings support conclusions from studies of dimensional models of internalizing and externalizing disorders, and extend them to person-centered approaches to classification.