Validity of sentinel lymph node biopsy by ICG fluorescence for early head and neck cancer.
Validity of sentinel lymph node biopsy by ICG fluorescence for early head and neck cancer.
复制标题
ICG 荧光前哨淋巴结活检对早期头颈癌的有效性。
作者：
Takehiro Nakamura;Yasunao Kogashiwa;H. Nagafuji;K. Yamauchi;N. Kohno
目标
本研究旨在评价吲哚青绿(ICG)荧光和放射性同位素(RI)联合应用或ICG单独应用于早期头颈癌患者前哨淋巴结(SLN)活检的有效性。
患者和方法
19例患者采用以下方法进行SLN活检。13例行单纯RI活检术，2例行ICG活检术，4例行ICG+RI活检术。每种方法检测SLN的时间，结合ICG和RI评价SLN的有效性。
结果
RI或ICG共检出41个SLN。ICG确定的所有SLN均可在术中定位。ICG和RI联合检测的SLN数目多于RI单独检测的SLN数目。其中一位单独接受RI活检的SLN患者在一年后被诊断为转移性淋巴结，然后接受了颈淋巴清扫术。ICG或ICG与RI联合检测SLN的平均检测时间明显短于RI单独检测。
结论
SLN活检结合ICG和RI使我们能够比单独使用RI更容易和更快地识别SLN。
AIM
This study was designed to assess the validity of sentinel lymph node (SLN) biopsy using either the combination of indocyanine green (ICG) fluorescence and radioisotope (RI) or ICG-alone in SLN mapping for early head and neck cancer patients.
PATIENTS AND METHODS
Nineteen patients received SLN biopsy with the following method. Thirteen patients received SLN biopsy with only RI, 2 patients with only ICG and 4 patients with the combination of ICG and RI. Detection time for each method of SLN biopsy was measured to evaluate the validity of SLN with the combination of ICG and RI.
RESULTS
A total of 41 SLNs were identified by RI or ICG. All SLNs identified by ICG could be localized intraoperatively. The number of SLNs identified by the combination of ICG and RI was greater than that of SLNs identified by RI-alone. One of the patients who underwent SLN biopsy by RI-alone was diagnosed with a metastatic lymph node one year later, then underwent neck dissection. Mean detection time for SLN biopsy with ICG or with the combination of ICG and RI tended to be shorter than that of RI-alone.
CONCLUSION
SLN biopsy with the combination of ICG and RI enabled us to identify SLNs more easily and rapidly than by using RI alone.
影响因子：
--
作者：
D. Morton;Wenger Dr;J. Wong;J. Economou;L. Cagle;Storm Fk;L. Foshag;A. Cochran
通讯作者：
D. Morton;Wenger Dr;J. Wong;J. Economou;L. Cagle;Storm Fk;L. Foshag;A. Cochran
影响因子：
158.5
作者：
Morton, Donald L.;Thompson, John F.;Wang, He-Jing
通讯作者：
Wang, He-Jing