The polychaete Platynereis dumerilli (Annelida):: a laboratory animal with spiralian cleavage, lifelong segment proliferation and a mixed benthic/pelagic life cycle
The polychaete Platynereis dumerilli (Annelida):: a laboratory animal with spiralian cleavage, lifelong segment proliferation and a mixed benthic/pelagic life cycle
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DOI：
10.1002/bies.10409
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发表时间：
2004-03-01
期刊：
影响因子：
4
通讯作者：
Dorresteijn, A
中科院分区：
文献类型：
--
作者：
Fischer, A;Dorresteijn, A
杜氏扁虫是一种间接发育的海洋多毛类环节动物，可以在实验室连续繁殖。在这里，我们描述其壮观的繁殖和发展，并解决一些开放的研究问题。卵子发生很容易研究，因为卵母细胞在体腔中漂浮生长。与其他模式螺的胚胎不同，Platynereis胚胎是透明的，可以深入了解细胞内的动态结构和过程，这些结构和过程伴随着普遍的各向异性分裂。胚胎、幼虫和后期阶段的细胞特化和差异基因表达的功能研究正在进行中。统一的躯干段的终身增殖资格Platynereis作为一个模型的基因表达和功能电路的研究这一过程。在比较环节动物和节肢动物之间的分割时，扁肛兽也可以成为一块垫脚石，因为它比其他模式环节动物更接近假定的祖先形态和发育风格。BioEssays 26：314-325，2004. (C)2004 Wiley Periodicals，Inc.
Platynereis dumerilli, a marine polychaetous annelid with indirect development, can be continuously bred in the laboratory. Here, we describe its spectacular reproduction and development and address a number of open research problems. Oogenesis is easily studied because the oocytes grow while floating in the coelom. Unlike the embryos of other model spiralians, the Platynereis embryo is transparent giving insight into the dynamic structures and processes inside the cells that accompany the prevailing anisotropic cleavages. Functional studies on cell specification and differential gene expression in embryos, larvae, and later stages are underway. Lifelong proliferation of uniform trunk segments qualifies Platynereis as a model for the study of gene expression and of the functional circuitry of this process. Platynereis can also become a stepping stone in the comparison of segmentation between annelids and arthropods because it comes closer to the putative ancestral morphology and style of development than other model annelids. BioEssays 26:314-325, 2004. (C) 2004 Wiley Periodicals, Inc.