Rhabdomyolysis in association with Duchenne's muscular dystrophy
Rhabdomyolysis in association with Duchenne's muscular dystrophy
复制标题
DOI：
10.1007/bf03013547
复制
发表时间：
1999-06-01
期刊：
影响因子：
--
通讯作者：
Sato, S
中科院分区：
文献类型：
--
作者：
Obata, R;Yasumi, Y;Sato, S
目的：提出一个病例横纹肌溶解发展的儿童与杜氏肌营养不良症的已知历史，麻醉包括七氟醚。临床特征：一名有杜氏肌营养不良病史的11岁男孩接受斜视麻醉修复术。麻醉剂由七氟醚和氧化亚氮组成，不使用肌肉松弛剂。他的术后过程因后跟疼痛和肌红蛋白尿的发展而复杂化。患者接受丹曲林钠治疗，两天后出院，无其他并发症。结论：既往未发现七氟醚麻醉与有杜氏肌营养不良病史的儿童急性横纹肌溶解有关。比如氟烷和异氟烷；在存在杜氏肌营养不良的情况下继续使用七氟醚应该受到质疑。
Purpose: To present a case of rhabdomyolysis which developed in a child with a known history of Duchenne's muscular dystrophy, following an anesthetic which included sevoflurane.Clinical features: An 11 yr old boy with a known history of Duchenne's muscular dystrophy underwent anesthesia for strabismus repair. The anesthetic consisted of sevoflurane and nitrous oxide without the use of a muscle relaxant. His postoperative course was complicated by a complaint of heel pain and the development of myoglobinuria. He was treated with dantrolene sodium and discharged home after two days, without further complication.Conclusion: Sevoflurane anesthesia has not been shown previously to be associated with the development of acute rhabdomyolysis in a child with a history of Duchenne's muscular dystrophy. As with halothane and isoflurane;the continued use of sevoflurane in the presence of Duchenne's muscular dystrophy should be questioned.